SARMs

SARMs (Selective Androgen Receptor Modulators) are chemical substances that exert their effects by binding to androgen receptors in various body tissues in different ways, stimulating or inhibiting them. They are not hormones, but substances that have similar effects to many of them, potentially providing anabolic benefits when used properly, but with less or no tendency to the unwanted side effects of hormonal products. Of course, results vary individually for a number of factors.

They were “invented” and studied since the 1940s, initially to help treat functional limitations related to ageing, chronic diseases, ease of falls and fractures, cancer-related cachexia and osteoporosis (see study: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2907129/).

They currently have several scientifically proven clinical applications (see study: https://www.ncbi.nlm.nih.gov/pubmed/30503797), among them treatments with better results in cases involving Alzheimer's, weight loss, mitochondrial energy and fatigue, fertility, erectile function, benign prostatic hyperplasia, hypogonadism, libido, muscle and bone mass, osteoporosis and recovery from injuries (etc.).

SARMs have been increasingly studied and used in various medical fields, such as urology, endocrinology and orthomolecular medicine. At the last Congress, at least four speakers addressed the topic, with results that are usually positive and increasingly promising, when used well, of course.

In my office, I already prescribe some of them, when indicated, regulated in Brazil (Andarine, Ibutamoren, Ligandrol, Ostarine, Stenabolic, YK11), using cycles of no more than 60 days and 8 weeks apart, according to the protocols and studies. The results have generally been good, always together with good lifestyle habits and what I explain in https://icaro.med.br/SAUDE/, and complement well the Integrative and Orthomolecular approaches in Medicine.