LATEST LIVE ON THE SUBJECT: T3 Hormone - What could be missing from your health?
T3 (Triiodothyronine or Liotyronine) is the thyroid hormone that is most important for metabolism, but it is one of the least evaluated and valued. When it's at optimum levels, it acts to reduce total cholesterol and circulating triglycerides (in a natural way) as well as healthy weight loss, fertility, providing energy and disposition for daily activities, better brain performance and a multitude of other benefits. It is important to clarify that every human being needs to produce T3 through its conversion from the T4 produced by the thyroid, throughout their lives, from childhood to old age.
However, recently another patient told me that her endocrinologist told her (wrongly, of course) that T3 “is useless”, that evaluating it “is nonsense” and that restoring it “is unnecessary and even dangerous”. Here's the tip: beware of health professionals who are out of date or “based” on low-quality knowledge. The study I show in the figure in this post says it well:
“MECHANISM OF ACTION
It is postulated that thyroid hormone exerts antidepressant efficacy through multiple mechanisms. Depression is associated with neuronal death, so a reduction in stress, atrophy and neuronal death would be associated with an antidepressant effect. T3 has been shown to increase gene expression by increasing levels of thyrotropin-releasing hormone (TRH), corticotrophin-releasing factor (CRH) and brain-derived neurotrophic factor (BDNF). There are changes in the sensitivity and transcription of serotonin (5-HT) receptors and possibly an increase in serotonin signaling after T3 administration. T3 administration also led to an increase in basal serotonin levels in the frontal cortex. There is a possible, but unclear, association between T3 and adrenergic transmission and activity of second messenger systems. It has not been shown to increase the concentrations of monoamine metabolites, even in patients whose depression improved after treatment with T3.”
“CONCLUSION OF THE STUDY: With proper initial and follow-up safety monitoring, increasing liothyronine (T3) can be a safe and effective treatment for unipolar depression.”
In my practice, I have seen hundreds of patients improve not only from depression, but also from various other symptoms and illnesses, when they improve their lifestyle habits (https://icaro.med.br/15habitos/), this is very important, and they optimize your hormone levels (including T3, even if replenished in low doses). Need I say more?
And how are your levels of T3 and free T3 (which is what matters most for metabolism)?
And remember: the lack of T3 is very common in cases of hypothyroidism! Find out more in https://icaro.med.br/hipotireoidismo/ e https://icaro.med.br/tireoide/.
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